Phenotype-genotype association analysis results for SNPs in Alpha 1A adrenergic receptor (ADRA1A)

Each thumbnail image below illustrates the results of multiple phenotype/genotype association comparisons between echocardiographic phenotypes in Framingham Heart Study Offspring subjects and their SNP genotypes. The 8 x 18 grid on the left illustrates associations analyzed with a variety of samples, covariates, and inheritance models. The 6 x 6 grid on the right illustrates gene-environment interactions between six phenotypes and six environmental factors (covariates), using the general inheritance model.

The color of a cell indicates the strength of the association (see the color key) based on the P-value of the comparison. Grids are sorted by physical map position in the UCSC Golden Path hg16 freeze.

Click on a phenotype-genotype association grid to view detailed data and graphs for that SNP.

PGA Grid
phenotype- genotype association	gene- environment interaction	SNP	Position	Type	Batch	HW Equilibrium
		rs4732845	chr: 26,618,183		5	pass
		rs2218280	chr: 26,619,046		5	pass
		rs4732847	chr: 26,621,071		5	pass
		rs1472346	chr: 26,623,304	3' of transcribed region	5	borderline
		rs1470221	chr8: 26,623,528	3' of transcribed region	3	pass
		rs2291775	chr: 26,633,178		5	pass
		rs4236678	chr: 26,640,276		5	pass
		hCV2696452	chr8: 26,646,516	3' of transcribed region	3	pass
		G2286a5	chr8: 26,649,582	missense	1	pass
		G2286a9	chr: 26,649,736		7	pass
		G2286a8	chr8: 26,649,938	missense	1	borderline
		hCV2696458	chr: 26,651,246		5	pass
		rs937351	chr8: 26,652,647	intronic	3	pass
		rs1908654	chr8: 26,665,153	intronic	3	pass
		rs4732874	chr: 26,667,522		5	borderline
		rs2036108	chr: 26,685,010	intronic	5	pass
		rs2055197	chr: 26,691,627		5	pass
		rs4732897	chr: 26,692,705		5	pass
		hCV2696515	chr: 26,695,812		5	pass
		hCV2696517	chr: 26,696,846		5	pass
		rs1390512	chr8: 26,705,138	intronic	2	pass
		hCV2696529	chr: 26,710,736	intronic	5	pass
		rs526302	chr: 26,712,605		5	pass
		rs498989	chr: 26,713,259	intronic	5	pass
		rs1383921	chr: 26,713,768		5	pass
		rs472151	chr: 26,714,277	intronic	5	pass
		hCV2696533	chr: 26,716,302		5	pass
		rs2170406	chr: 26,716,704		5	pass
		hCV2959210	chr: 26,717,165	intronic	5	pass
		rs574647	chr: 26,718,967	intronic	5	pass
		rs4545110	chr: 26,719,957		5	pass
		rs495495	chr8: 26,720,078	intronic	3	pass
		rs556793	chr8: 26,720,977	intronic	2	pass
		rs3102087	chr: 26,721,847		5	pass
		rs558455	chr8: 26,727,491	intronic	2	pass
		rs486354	chr: 26,732,200		5	pass
		rs544104	chr8: 26,733,900	intronic	3	pass
		rs544215	chr: 26,733,938	intronic	5	pass
		rs580739	chr8: 26,735,617	intronic	2	pass
		rs522996	chr: 26,737,141	intronic	5	pass
		rs538378	chr8: 26,738,625	intronic	2	pass
		hCV2696566	chr: 26,739,727		5	pass
		G2286a11	chr8: 26,743,658	missense	3	pass
		G2286a3	chr8: 26,743,798	missense	1	pass
		G2286a1	chr8: 26,743,937	missense	1	pass
		rs922733	chr: 26,749,280	5' of transcribed region	5	pass
		rs4639517	chr: 26,749,945		5	pass
		rs559920	chr: 26,750,066		5	pass
		rs536220	chr: 26,750,347	5' of transcribed region	5	pass
		rs483392	chr8: 26,751,651	5' of transcribed region	2	borderline
		rs498246	chr8: 26,754,021	5' of transcribed region	3	pass
		rs489223	chr8: 26,758,899	5' of transcribed region	2	pass

Color Key:

no P-value

0.05≤P≤ 1.0

0.01≤P<0.05

0.001≤P<0.01

0.0001≤P<0.001

P < 0.0001