Phenotype-genotype association analysis results for SNPs in Angiotensin Converting Enzyme (ACE)

Each thumbnail image below illustrates the results of multiple phenotype/genotype association comparisons between echocardiographic phenotypes in Framingham Heart Study Offspring subjects and their SNP genotypes. The 8 x 18 grid on the left illustrates associations analyzed with a variety of samples, covariates, and inheritance models. The 6 x 6 grid on the right illustrates gene-environment interactions between six phenotypes and six environmental factors (covariates), using the general inheritance model.

The color of a cell indicates the strength of the association (see the color key) based on the P-value of the comparison. Grids are sorted by physical map position in the UCSC Golden Path hg16 freeze.

Click on a phenotype-genotype association grid to view detailed data and graphs for that SNP.

PGA Grid
phenotype- genotype association	gene- environment interaction	SNP	Position	Type	Batch	HW Equilibrium
		G9840a6	chr17: 62,031,144	missense	1	pass
		hCV1247703	chr: 62,031,600	intronic	4	pass
		hCV1247706	chr: 62,033,294	silent	4	pass
		rs4309	chr17: 62,033,294	silent	2	pass
		WIPGA_03_433	chr: 62,033,872		6	pass
		hCV1247707	chr17: 62,034,134	intronic	2	pass
		rs4316	chr17: 62,035,680	intronic	2	pass
		rs4329	chr: 62,036,829		9	pass
		G9840a30_R	chr: 62,047,863		9	pass
		rs9896208	chr: 62,049,480		9	pass
		rs12449782	chr: 62,049,620		9	pass
		rs4968653	chr: 62,052,469		4	pass
		rs7221678	chr: 62,052,983		9	pass
		rs4459610	chr: 62,058,091		4	pass

Color Key:

no P-value

0.05≤P≤ 1.0

0.01≤P<0.05

0.001≤P<0.01

0.0001≤P<0.001

P < 0.0001