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PI3k Home Physiology Microarray Data Related Literature Project 1 Home

Related Literature

Bi,L., Okabe,I., Bernard,D.J., Wynshaw-Boris,A. and Nussbaum,R.L. (1999) Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110 subunit of phosphoinositide 3-kinase. J. Biol. Chem., 274, 10963–10968.[Abstract/Full Text]

Bohni,R., Riesgo-Escovar,J., Oldham,S., Brogiolo,W., Stocker,H., Andruss,B.F., Beckingham,K. and Hafen,E. (1999) Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell, 97, 865–875.[Medline]

Burgering,B.M. and Coffer,P.J. (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature, 376, 599–602.[Medline]

Chan,T.O., Rittenhouse,S.E. and Tsichlis,P.N. (1999) Akt/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation. Annu. Rev. Biochem., 68, 965–1014.[Abstract/Full Text]

Conlon,I. and Raff,M. (1999) Size control in animal development. Cell, 96, 235–244.[Medline]

Coolican,S.A., Samuel,D.S., Ewton,D.Z., McWade,F.J. and Florini,J.R. (1997) The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J. Biol. Chem., 272, 6653–6662.[Abstract/Full Text]

DeChiara,T.M., Efstratiadis,A. and Robertson,E.J. (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature, 345, 78–80.[Medline]

Dhand,R. et al. (1994) PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J., 13, 511–521.[Abstract]

Franke,T.F., Kaplan,D.R. and Cantley,L.C. (1997) PI3K: downstream AKTion blocks apoptosis. Cell, 88, 435–437.[Medline]

Franke,T.F., Kaplan,D.R., Cantley,L.C. and Toker,A. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science, 275, 665–668.[Abstract/Full Text]

Fruman,D.A., Meyers,R.E. and Cantley,L.C. (1998) Phosphoinositide kinases. Annu. Rev. Biochem., 67, 481–507.[Abstract/Full Text]

Fruman,D.A., Snapper,S.B., Yballe,C.M., Davidson,L., Yu,J.Y., Alt,F.W. and Cantley,L.C. (1999) Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85 . Science, 283, 393–397.[Abstract/Full Text]

Hayashi,K., Saga,H., Chimori,Y., Kimura,K., Yamanaka,Y. and Sobue,K. (1998) Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase. J. Biol. Chem., 273, 28860–28867.[Abstract/Full Text]

Hu,Q., Klippel,A., Muslin,A.J., Fantl,W.J. and Williams,L.T. (1995) Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science, 268, 100–102.[Medline]

Izumo,S. and Shioi,T. (1998) Cardiac transgenic and gene-targeted mice as models of cardiac hypertrophy and failure: a problem of (new) riches. J. Card. Fail., 4, 263–270.[Medline]

Jiang,B.H., Aoki,M., Zheng,J.Z., Li,J. and Vogt,P.K. (1999) Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B. Proc. Natl Acad. Sci. USA, 96, 2077–2081.[Abstract/Full Text]

Klippel,A., Escobedo,J.A., Hirano,M. and Williams,L.T. (1994) The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol. Cell. Biol., 14, 2675–2685.[Abstract]

Klippel,A., Reinhard,C., Kavanaugh,W.M., Apell,G., Escobedo,M.A. and Williams,L.T. (1996) Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol. Cell. Biol., 16, 4117–4127.[Abstract]

Leevers,S.J., Weinkove,D., MacDougall,L.K., Hafen,E. and Waterfield,M.D. (1996) The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J., 15, 6584–6594.[Abstract]

McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Kang PM, Izumo S. Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21): 12355-60. Epub 2003 Sep 24. [Abstract]

Misawa H, Ohtsubo M, Copeland NG, Gilbert DJ, Jenkins NA, Yoshimura A. Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain. Biochem Biophys Res Commun. 1998 Mar 17;244(2):531-9.

Montagne,J., Stewart,M.J., Stocker,H., Hafen,E., Kozuma,S.C. and Thomas,G. (1999) Drosophila S6 kinase: a regulator of cell size. Science, 285, 2126–2129.[Abstract/Full Text]

Naga Prasad SV, Esposito G, Mao L, Koch WJ, Rockman HA. Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J Biol Chem. 2000 Feb 18;275(7):4693-8.

Rameh,L.E. and Cantley,L.C. (1999) The role of phosphoinositide 3-kinase lipid products in cell function. J. Biol. Chem., 274, 8347–8350.[Full Text]

Thomas,G. (1999) Drosophila S6 kinase: a regulator of cell size. Science, 285, 2126–2129.[Abstract/Full Text]

Toker,A. and Cantley,L.C. (1997) Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature, 387, 673–676.[Medline]

Vanhaesebroeck,B., Leevers,S.J., Panayotou,G. and Waterfield,M.D. (1997) Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci., 22, 267–272.[Medline]

Verdu,J., Buratovich,M.A., Wilder,E.L. and Birnbaum,M.J. (1999) Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. Nature Cell Biol., 1, 500–506.

Weinkove,D., Neufeld,T.P., Twardzik,T., Waterfield,M.D. and Leevers,S.J. (1999) Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr. Biol., 9, 1019–1029.[Medline]



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